[Mark44]

2020 softail, changed them in 22, then in 24.

I wouldn't think that the plugs would need to be changed that often.

Do you see anything wrong with them? I could not.

The gap looks a bit large to me. Did you gap the plugs before putting them in?

After 85mpg it started to ping, knock,

Do you mean 85 mph or 85 miles? Before clicking the "Post reply" button, it would be a good idea to take a look at what you're about to post to eliminate obvious errors like the above.

85 MPG? Man, that thing is running awful lean.

What test did you perform to determine that one has an internal break?

A continuity check with a multimeter set on the ohm scale could be used, but the OP neglected to tell us this.