Cap the vacuum line off, no problem, small plastic caps available @ auto parts stores.
I run 44 & 175 on my stock 80"shovel with the with idle mixture screw
turned out 2 turns.
If the carb is bone stock you'll have to expose the idle mixture screw by popping out the small plug on the Left side bottom of the carb.
Also you'll need an adapter to fit the CV carb to your manifold.
These are available on Ebay @ about 30.00.
You should be good to go for around $100-125.
You'll need new cables as well. Hook up the enrichner also, these carbs don't have a "real" choke, that's what the enrichner is for.
Great carb with the accelerator pump, great throttle response.
Couldn't be happier. Also you may want to check www.shovelhead.us
for more info. Good luck!